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TECHNOLOGY | 15.11.2024

Indium detects lung cancer in exhaled breath

3-D-Illustration einer Lunge und Atemwege Lungenkrebs Indium

There is something in the air. We all know this expression as a metaphor for a threatening but not clearly tangible scenario. One example could be an undetected serious illness such as lung cancer. However, analyzing that air could now provide the key to early diagnosis and improved chances of recovery. This is made possible by a new sensor technology discovered by Chinese researchers.

Indium and platinum detect reduced isoprene levels

The breath of people suffering from lung cancer shows a reduced concentration of the hydrocarbon isoprene. This makes it possible to diagnose the disease through an analysis of exhaled air. A research team at China’s Zhejiang University was able to implement this practically using a portable nanosensor built with metals such as platinum and indium oxide.

Fantastic results thanks to more sensitive sensors

Although the device is still in the testing phase, it is already delivering fantastic results. It is significantly more sensitive than existing isoprene sensors and can detect the substance at levels as low as two parts per billion. The device is extremely selective and can effectively distinguish isoprene from other volatile substances. For example, it tolerates the natural moisture content of exhaled breath.

Possible breakthrough in non-invasive screening

In contrast to its predecessor models, the new device is not only based on indium oxide but also uses platinum nanoclusters as a catalyst to activate isoprene detection. According to the researchers, this new technology could represent a breakthrough for non-invasive screening. Once the device is commercialized, its manufacturers will likely require a significant amount of indium and platinum. Until then, research continues diligently with both metals.

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